Dr Carney received his Ph.D. in Medical Microbiology and Infectious Diseases, Thomas Jefferson Medical School and from 1978-1982 was a Harvard/NIH Fellow in the Dept of Infectious Diseases at Mass General where he trained in virology and was one of the early scientists investigating HIV immunological responses. In 1982, Dr Carney joined DuPont Medical Products. Dr Carney was the first to discover and patent the circulating extracellular domain of HER-2. In 1991, Dr Carney joined Oncogene Science as Vice President R&D and eventually became President of Oncogene Science Diagnostics.
When the company was acquired by Bayer Diagnostics and Bayer Healthcare (BHC) and Dr. Carney continued as President and Head of the Oncogene Science. In 2001, Dr Carney received the Otto Bayer Medal from BHC for the discovery of the HER-2 protein and blood test. At Oncogene Science, Dr. Carney was responsible for R&D, GMP/ISO manufacturing, QMS and international commercialization of numerous blood based and tissue-based biomarkers to guide targeted oncology therapies.
In addition to leading the team that obtained FDA clearance of serum HER-2 as a Class 2 IVD, Dr Carney was responsible for a new CPT code and has published over 250 articles and abstracts and has been awarded over 30 patents. In 2010, Dr Carney joined On-Q-ity as CSO and in 2011 became CEO. Dr Carney and his team developed a unique and proprietary platform which captured circulating tumor cells based on physical size and affinity capture. In Feb 2012, Dr Carney re-joined Wilex (formerly Oncogene Science) as CSO and in Sept 2013 became SVP at Nuclea Biotechnologies when Wilex was acquired.
In 2015, Dr Carney Founded Walt Carney Biomarkers Consulting and consults/advises companies with respect to biomarkers for drug development, diagnostic product development, product commercialization, and strategies for biomarker selection in the areas of oncology, immuno-oncology, neurology, and infectious disease.
Dr Carney has designed and implemented biomarker strategies for patient stratification and monitoring of a variety of personalized cancer therapies, including small molecule therapies, Mab-based immunotherapies such as checkpoint inhibitors (Keytruda), anti-HER-2 therapies (Trastuzumab), or immunotherapies such as autologous T cells. During this time, Dr Carney has also advised start-up biotechnology companies on investor presentations, fundraising, and product positioning strategies. Dr Carney has also provided insight and guidance with respect to product development and commercialization strategies, according to FDA and CLIA guidelines.